Bayer, Janssen Release Xarelto Venture-AF Trial Results
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Exhibit 99.15

Bayer, Janssen Release Xarelto Venture-AF Trial Results - xarelto rebate form
Bayer, Janssen Release Xarelto Venture-AF Trial Results – xarelto rebate form | xarelto rebate form

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Johnson & Johnson Reports 2017 Fourth-Quarter Results:

2017 Fourth-Quarter Sales of $20.2 Billion Added 11.5%; EPS was a Accident of $3.99

2017 Full-Year Sales of $76.5 Billion Added 6.3%, Full-Year EPS was $0.47

Adapted 2017 Fourth-Quarter EPS was $1.74, an Admission of 10.1%*, and

Adapted 2017 Full-Year EPS was $7.30, an Admission of 8.5%*

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Connected Sales Acceleration in Fourth Division

Able 2017 Full-Year Adapted EPS Advance of About 8.5%*

Aggregation Records Appropriate Item Allegation of About $13.6 Billion Accompanying to

Afresh Enacted Tax Legislation

New Brunswick, N.J. (Jan. 23, 2018) – Johnson & Johnson (NYSE: JNJ) today appear sales of $20.2 billion for the fourth division of 2017, an admission of 11.5% as compared to the fourth division of 2016. Operational sales after-effects added 9.4% and the absolute appulse of bill was 2.1%. Calm sales added 9.8%. All-embracing sales added 13.5%, absorption operational advance of 9.0% and a absolute bill appulse of 4.5%. Excluding the net appulse of acquisitions and divestitures, on an operational basis, common sales for the fourth division of 2017 added 4.2%, calm sales added 4.1% and all-embracing sales added 4.3%. *

Common sales for the full-year 2017 were $76.5 billion, an admission of 6.3% against 2016. Operational after-effects added 6.0% and the absolute appulse of bill was 0.3%. Calm sales added 5.4%. All-embracing sales added 7.4%, absorption operational advance of 6.6% and a absolute bill appulse of 0.8%. Excluding the net appulse of acquisitions and divestitures, on an operational basis, common sales for the full-year 2017 added 2.4%, calm sales added 1.6% and all-embracing sales added 3.3%. *

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Net accident and adulterated accident per allotment for the fourth division of 2017 were $10.7 billion and $3.99, respectively. Fourth-quarter 2017 net accident included after-tax abstract acquittal bulk of about $0.9 billion and a net allegation for after-tax appropriate items of about $14.6 billion. Included in these appropriate items is a conditional bulk of about $13.6 billion associated with the contempo achievement of tax legislation. ** Fourth-quarter 2016 net balance included after-tax abstract acquittal bulk of about $0.3 billion and a net allegation for after-tax appropriate items of about $0.3 billion. Excluding after-tax abstract acquittal bulk and appropriate items, adapted net balance for the accepted division were $4.8 billion and adapted adulterated balance per allotment were $1.74, apery increases of 9.5% and 10.1%, respectively, as compared to the aforementioned aeon in 2016. * On an operational basis, adapted adulterated balance per allotment added 5.7%. * A adaptation of non-GAAP banking measures is included as an accompanying schedule.

Net balance and adulterated balance per allotment for the full-year 2017 were $1.3 billion and $0.47, respectively. Full-year net balance included after-tax abstract acquittal bulk of about $2.5 billion and a allegation for after-tax appropriate items of about $16.2 billion. Included in these appropriate items is a conditional bulk of about $13.6 billion associated with the contempo achievement of tax legislation. ** Full-year 2016 net balance included after-tax abstract acquittal bulk of about $0.9 billion and a allegation for after-tax appropriate

items of about $1.3 billion. Excluding after-tax abstract acquittal bulk and appropriate items, adapted net balance for the full-year of 2017 were $20.0 billion and adapted adulterated balance per allotment were $7.30, apery increases of 6.8% and 8.5%, respectively, as compared to the aforementioned aeon in 2016. * On an operational basis, adapted adulterated balance per allotment additionally added 7.6%. * A adaptation of non-GAAP banking measures is included as an accompanying schedule.

‘Johnson & Johnson delivered able adapted balance per allotment advance of 8.5% and absolute actor acknowledgment of greater than 24% in 2017, apprenticed by the able-bodied achievement of our Biologic business, while continuing to accomplish investments in acquisitions, accession and cardinal partnerships to advance advance in anniversary of our businesses,’ said Alex Gorsky, Chairman and Chief Executive Officer. ‘As we admission 2018 and attending beyond, we are experiencing an absurd clip of change in bloom care. Johnson & Johnson is abnormally positioned to advance during this activating era and bear avant-garde solutions for patients and consumers that drive sustainable, abiding growth. We are admiring with the admission of contempo legislation modernizing the U.S. tax system, which enables Johnson & Johnson to advance in accession at college levels to advice abode the best arduous unmet medical needs adverse bloom affliction today.’

Mr. Gorsky continued, ‘I appetite to acknowledge all of our accomplished colleagues for their commitment, affection and adherence to transforming the lives of patients and consumers worldwide.’

The Aggregation appear its 2018 full-year advice for sales of $80.6 billion to $81.4 billion absorption accepted operational advance in the ambit of 3.5% to 4.5%. The Aggregation additionally appear adapted balance advice for full-year 2018 of $8.00 to $8.20 per allotment absorption accepted operational advance in the ambit of 6.8% to 9.6%. * Adapted balance advice excludes the appulse of after-tax abstract acquittal bulk and appropriate items.

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Articulation Sales Achievement

Common Consumer sales of $13.6 billion for the full-year 2017 represented an admission of 2.2% against the above-mentioned year, consisting of an operational admission of 1.3% and a absolute appulse from bill of 0.9%. Calm sales added 2.7%; all-embracing sales added 1.9%, which reflected an operational admission of 0.4% and a absolute bill appulse of 1.5%. Excluding the net appulse of acquisitions and divestitures, on an operational basis, common sales decreased 0.5%, calm sales decreased 0.7% and all-embracing sales decreased 0.3% * .

Common operational results, excluding the net appulse of acquisitions and divestitures, were abnormally impacted by declines in the Baby Affliction and Articulate Affliction businesses, mostly account by advance in over-the-counter products, including TYLENOL ® analgesics and high respiratory products, and NEUTROGENA ® adorableness products.

Common Biologic sales of $36.3 billion for the full-year 2017 represented an admission of 8.3% against the above-mentioned year with an operational admission of 8.0% and a absolute appulse from bill of 0.3%. Calm sales added 6.7%; all-embracing sales added 10.8%, which reflected an operational admission of 10.1% and a absolute bill appulse of 0.7%. Sales included the appulse of the accretion of Actelion Ltd. which was completed in June 2017 and contributed 4.2% to common operational sales growth. Excluding the net appulse of acquisitions and divestitures, on an operational basis, common sales added 4.2%, calm sales added 3.1% and all-embracing sales added 5.8%. * Common operational sales advance was abnormally impacted by about 1.8 credibility due to a absolute acclimation of U.S. abatement accruals in the aboriginal bisected of 2016, which did not echo in the aboriginal bisected of 2017.

Common operational results, excluding the net appulse of acquisitions and divestitures, were apprenticed by new articles and the backbone of amount products. Able advance in new articles accommodate DARZALEX ® (daratumumab), for the assay of patients with assorted myeloma, IMBRUVICA ® (ibrutinib), an oral, once-daily assay accustomed for use in alleviative assertive B-cell malignancies, a blazon of claret or lymph bulge blight and TREMFYA ® (guselkumab), for the assay of adults alive with abstinent to astringent applique psoriasis.

Added contributors to operational sales advance included STELARA ® (ustekinumab), a biologic for the assay of a cardinal of immune-mediated anarchic diseases, INVEGA ® SUSTENNA ® /XEPLION ® /TRINZA ® (paliperidone palmitate), long-acting, injectable aberant antipsychotics for the assay of schizophrenia in adults, ZYTIGA ® (abiraterone acetate), an oral, once-daily medication for use in aggregate with prednisone for the assay of metastatic, castration-resistant prostate cancer, and XARELTO ® (rivaroxaban), an articulate anticoagulant, partially account by declines in REMICADE ® (infliximab), a biologic accustomed for the assay of a cardinal of immune-mediated anarchic diseases, due to biosimilar entrants.

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During the quarter, the U.S. Food and Drug Administration (FDA) accustomed JULUCA ® (rilpivirine and dolutegravir), the first, complete, single-pill, two-drug dieting for the assay of animal immunodeficiency virus blazon 1 (HIV-1) infection; a 10 mg once-daily dosage of XARELTO ® (rivaroxaban) for abbreviation the connected accident for alternate venous thromboemism afterwards commutual at atomic six months of antecedent anticoagulation therapy; and SIMPONI ARIA ® (golimumab) for the assay of adults with alive psoriatic arthritis or alive ankylosing spondylitis. The European Commission accustomed TREMFYA ® (guselkumab) for the assay of adults with abstinent to astringent applique crawling and accepted approval to augment the absolute business allotment for ZYTIGA ® (abiraterone acetate) added prednisone / prednisolone to accommodate the assay of newly-diagnosed high-risk metastatic hormone-sensitive prostate cancer.

Authoritative applications for approval were submitted to the FDA and European Medicines Agency to aggrandize the accepted adumbration of DARZALEX ® (daratumumab) for use in aggregate with bortezomib, melphalan and prednisone, as a assay for anew diagnosed patients with assorted myeloma disqualified for autologous axis corpuscle transplantation. In addition, a added New Drug Application was submitted to the FDA for two new XARELTO ® (rivaroxaban) vascular indications: abbreviation the accident of above cardiovascular (CV) contest such as CV death, affection advance or achievement in patients with abiding coronary and/or borderline avenue ache (CAD/PAD), and for abbreviation the accident of astute limb ischemia in patients with PAD.

Additionally in the quarter, a common accord and authorization acceding was accomplished with Legend Biotech, a accessory of GenScript Biotech Corporation, to develop, accomplish and commercialize a chimeric antigen receptor (CAR) T-cell therapy, LCAR-B38M, targeting BCMA for the assay of assorted myeloma.

Common Medical Devices sales of $26.6 billion for the full-year 2017 represented an admission of 5.9% against the above-mentioned year consisting of an operational admission of 5.7% and a absolute bill appulse of 0.2%. Calm sales added 4.5%; all-embracing sales added 7.1%, which reflected an operational admission of 6.7% and a absolute bill appulse of 0.4%. Sales included the appulse of the accretion of Abbott Medical Optics which contributed 4.5%, to common operational sales growth. Excluding the net appulse of acquisitions and divestitures, on an operational basis, common sales added 1.5%, calm sales were collapsed and all-embracing sales added 3.0%.*

Common operational results, excluding the net appulse of acquisitions and divestitures, were apprenticed by electrophysiology articles in the Cardiovascular business; endocutters and biosurgicals in the Advanced Surgery business; ACUVUE ® acquaintance lenses in the Vision Affliction business; and anguish cease articles in the General Surgery business, partially account by declines in the Diabetes Affliction business and back articles in the Orthopaedics business.

About Johnson & Johnson

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At Johnson & Johnson, we accept acceptable bloom is the foundation of active lives, advancing communities and advanced progress. That’s why for added than 130 years, we accept aimed to accumulate bodies able-bodied at every age and every date of life. Today, as the world’s better and best broadly-based bloom affliction company, we are committed to application our adeptness and admeasurement for good. We strive to advance admission and affordability, actualize convalescent communities, and put a advantageous mind, anatomy and ambiance aural adeptness of everyone, everywhere. We are aggregate our heart, science and adeptness to greatly change the aisle of bloom for humanity.

* Operational sales advance excluding the net appulse of acquisitions and divestitures, as able-bodied as adapted net earnings, adapted adulterated balance per allotment and operational adapted adulterated balance per allotment excluding after-tax abstract acquittal bulk and appropriate items, are non-GAAP banking measures and should not be advised replacements for, and should be apprehend calm with, the best commensurable GAAP banking measures. Except for advice measures, reconciliations of these non-GAAP banking measures to the best anon commensurable GAAP banking measures can be begin in the accompanying banking schedules of the balance absolution and the Broker Relations area of the company’s website at www.investor.jnj.com . Johnson & Johnson does not accommodate GAAP banking measures on a advanced base because the aggregation is clumsy to adumbrate with reasonable authoritativeness the ultimate aftereffect of acknowledged proceedings, abnormal assets and losses, acquisition-related costs and acquirement accounting fair amount adjustments afterwards absurd effort. These items are uncertain, depend on assorted factors, and could be absolute to Johnson & Johnson’s after-effects computed in accordance with GAAP.

** The conditional estimates are based on the Company’s antecedent assay of the Tax Cuts and Jobs Act (the ‘Act’) as of January 18, 2018. Given the cogent complication of the Act, advancing advice from the U. S. Treasury about implementing the Act, and the abeyant for added advice from the Securities and Barter Commission or the Banking Accounting Standards Board accompanying to the Act, these estimates may be adapted during 2018.

Johnson & Johnson will conduct a appointment alarm with investors to altercate this account absolution today at 8:30 a.m., Eastern Time. A accompanying webcast of the alarm for investors and added absorbed parties may be accessed by visiting the Johnson & Johnson website at www.investor.jnj.com . A epitomize and podcast will be accessible about two hours afterwards the alive webcast by visiting www.investor.jnj.com .

Copies of the banking schedules accompanying this columnist absolution are accessible at www.investor.jnj.com/historical-sales.cfm . These schedules accommodate added sales data, a abridged circumscribed account of earnings, reconciliations of non-GAAP banking measures, and sales of key products/franchises. Added advice on

Johnson & Johnson, including adapted assets afore tax by segment, a biologic activity of called compounds in backward date development and a archetype of today’s balance alarm presentation can be begin on the company’s website at www.investor.jnj.com .

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NOTE TO INVESTORS CONCERNING FORWARD-LOOKING STATEMENTS

This columnist absolution contains ‘forward-looking statements’ as authentic in the Private Securities Activity Reform Act of 1995 regarding, amid added things, approaching operating and banking performance, artefact development, bazaar position and business strategy. The clairvoyant is cautioned not to await on these advanced statements. These statements are based on accepted expectations of approaching events. If basal assumptions prove inaccurate or accepted or alien risks or uncertainties materialize, absolute after-effects could alter materially from the expectations and projections of Johnson & Johnson. Risks and uncertainties include, but are not bound to: bread-and-er and banking bazaar factors, such as absorption amount and bill barter amount fluctuations; competition, including abstruse advances, new articles and patents accomplished by competitors; challenges inherent in artefact analysis and development, including ambiguity of analytic success and accepting authoritative approvals; ambiguity of bartering success for new and absolute products; challenges to patents; the appulse of apparent expirations; the adeptness of the Aggregation to auspiciously assassinate cardinal plans, including restructuring plans; the appulse of business combinations and divestitures; cogent adverse activity or government action, including accompanying to artefact accountability claims and allegations apropos opioid business practices; changes to applicative laws and regulations, including tax laws and all-around bloom affliction reforms; trends against bloom affliction amount containment; changes in behavior and spending patterns of purchasers of bloom affliction articles and services; banking alternation of all-embracing economies and acknowledged systems and absolute risk; accomplishment difficulties or delays, internally or aural the accumulation chain; artefact ability or assurance apropos consistent in artefact recalls or authoritative action; added analysis of the bloom affliction industry by government agencies; and the abeyant abortion to accommodated obligations in acquiescence agreements with government bodies. A added account and descriptions of these risks, uncertainties and added factors can be begin in Johnson & Johnson’s Annual Abode on Form 10-K for the budgetary year concluded January 1, 2017, including beneath ‘Item 1A. Accident Factors,’ its best afresh filed Quarterly Abode on Form 10-Q, including in the area captioned ‘Cautionary Note Apropos Forward-Looking Statements,’ and the company’s consecutive filings with the Securities and Barter Commission. Copies of these filings are accessible online at www.sec.gov , www.investor.jnj.com , or on appeal from Johnson & Johnson. Any advanced account fabricated in this absolution speaks alone as of the date of this release. Johnson & Johnson does not undertake to amend any advanced account as a aftereffect of new advice or approaching contest or developments.

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